Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235200 | 0.78 | KDM4E (0.37) | PDE10AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL22598457 | 0.78 | PDE5A (0.35) | PDE10AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL3217372 | 0.78 | KDM4E (0.35) | PDE10AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL23664426 | 0.78 | PDE10A (0.35) | PDE10AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL18307332 | 0.74 | KDM4E (0.43) | PDE10AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL24457882 | 0.72 | KDM4E (0.39) | PDE10AKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL21240997 | 0.72 | HSD17B10 (0.48) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL3208142 | 0.72 | SMPD3 (0.41) | KDM4EHPGDALDH1A1HSD17B10NPSR1 | |
| SCHEMBL8738635 | 0.72 | ALDH1A1 (0.37) | PDE10AKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL21241177 | 0.71 | S1PR1 (0.37) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143677-A1 | FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-22 | — | — | WO | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |