Sugi Predict

Sugi Predict / Compounds / SCHEMBL2124178

SCHEMBL2124178

SCHEMBL2124178

CC1(C(=O)O)CCCCC1N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR3 O14843 1/20 0.36
▸ F10 P00742 2/20 0.35
▸ PTPN1 P18031 2/20 0.34
▸ MMP2 P08253 1/20 0.34
▸ PTPN2 P17706 1/20 0.34
▸ CDC25B P30305 1/20 0.34
▸ MAPK1 P28482 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ NFKB1 P19838 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ THPO P40225 1/20 0.33
▸ STAT6 P42226 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ GMNN O75496 1/20 0.33
▸ MTOR P42345 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2124898 1.00 FFAR3 (0.36) FFAR3F10PTPN1MMP2PTPN2
SCHEMBL2124175 1.00 FFAR3 (0.36) FFAR3F10PTPN1MMP2PTPN2
SCHEMBL17784260 1.00 FFAR3 (0.36) FFAR3F10PTPN1MMP2PTPN2
SCHEMBL9970858 1.00 FFAR3 (0.36) FFAR3F10PTPN1MMP2PTPN2
SCHEMBL10303638 1.00 FFAR3 (0.36) FFAR3F10PTPN1MMP2PTPN2
SCHEMBL2124177 1.00 FFAR3 (0.36) FFAR3F10PTPN1MMP2PTPN2
Hydrochloric Acid SCHEMBL2200798 0.96 LMNA (0.35) FFAR3F10PTPN1MMP2PTPN2
Hydrochloric Acid SCHEMBL2200794 0.96 LMNA (0.35) FFAR3F10PTPN1MMP2PTPN2
Acetic Acid SCHEMBL2201148 0.94 POLB (0.34) FFAR3F10PTPN1MMP2PTPN2
Acetic Acid SCHEMBL2201138 0.94 POLB (0.34) FFAR3F10PTPN1MMP2PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100367949-C Melanin extinguisher OGA RES INC (JP) 2008-02-13 — — CN claimed
EP-3427738-B1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMA (US) 2021-12-01 — — EP disclosed
US-10874673-B2 Inhibitors of influenza viruses replication VERTEX PHARMACEUTICALS INCORPORATED (US) 2020-12-29 — — US disclosed
CN-104922128-B Inhibitors of influenza virus replication 沃泰克斯药物股份有限公司 2019-12-20 — — CN disclosed
CN-110540538-A Inhibitors of influenza virus replication VERTEX PHARMA 2019-12-06 — — CN disclosed
US-20190151314-A1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMACEUTICALS INCORPORATED 2019-05-23 — — US disclosed
EP-3427738-A1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION Vertex Pharmaceuticals Incorporated (US) 2019-01-16 — — EP disclosed
CN-104940202-B Inhibitors of influenza viruses replication 沃泰克斯药物股份有限公司 2018-10-16 — — CN disclosed
US-10039762-B2 Inhibitors of influenza viruses replication VERTEX PHARMACEUTICALS INCORPORATED (US) 2018-08-07 — — US disclosed
EP-3141252-B1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMA (US) 2018-07-25 — — EP disclosed
CN-1681490-A Melanin extinguisher OGA RES INC (JP) 2005-10-12 — — CN disclosed
CN-1525907-A Continuous biaxial stretching polypropylene porous membrane and preparation method thereof �ձ�������ʽ���� 2004-09-01 — — CN disclosed
CN-1487814-A Process for producing dry water 株式会社资生堂 2004-04-07 — — CN disclosed
CN-1111161-C Diacetal composition, process for preparation of same, nucleating agent for polyolefins contg. same, polyolefin resin compositions, and moldings NEW JAPAN CHEM CO LTD (JP) 2003-06-11 — — CN disclosed
CN-1418111-A Novel Ligands and method for preparing same NAT UNIV SINGAPORE (SG) 2003-05-14 — — CN disclosed
JP-2002195995-A BLOOD COAGULATION ACCELERANT AND CONTAINER FOR BLOOD TEST SEKISUI CHEM CO LTD 2002-07-10 — — JP disclosed
CN-1260345-A Hydrazide compound, its preparing method and medicine compositions thereof ADIR ET COMPANGIE (FR) 2000-07-19 — — CN disclosed
CN-1241190-A Diacetal composition, process for producing the same, polyolefin nucleating agent containing said composition, polyolefin resin composition and molded article NEW JAPAN CHEM CO LTD (JP) 2000-01-12 — — CN disclosed
CN-1137378-A Use of HCPSH2 specific compounds to enhance erythropoiesis SMITHKLINE BEECHAM CORP (US) 1996-12-11 — — CN disclosed
CN-1122577-A Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders DU PONT MERCK PHARMA (US) 1996-05-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190151314-A1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION ACE, IRF3, ACE2 FFAR3 4735/4885F10 1105/4885PTPN1 2522/4885
US-10874673-B2 Inhibitors of influenza viruses replication ACE, IRF3, ACE2 FFAR3 4735/4885F10 1105/4885PTPN1 2522/4885
US-10039762-B2 Inhibitors of influenza viruses replication ACE, IRF3, ACE2 FFAR3 4735/4885F10 1105/4885PTPN1 2522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.