Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 7/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517454 | 0.82 | TNF (0.43) | HTR2CHTR2AHDAC3HDAC1HDAC6 | |
| SCHEMBL21241821 | 0.82 | TNF (0.43) | HTR2CHTR2AHDAC3HDAC1HDAC6 | |
| SCHEMBL22971727 | 0.82 | HTR1D (0.44) | HTR2CHTR2AHTR1DHDAC3HDAC1 | |
| SCHEMBL23729375 | 0.80 | HTR2A (0.41) | HTR2CHTR2AHDAC3HDAC1HDAC6 | |
| SCHEMBL20786925 | 0.75 | HTR2C (0.44) | HTR2CHTR2AHTR1DHDAC3HDAC1 | |
| SCHEMBL16939364 | 0.75 | HTR2C (0.63) | HTR2CHTR2AHTR1DHTR6 | |
| SCHEMBL18914238 | 0.74 | HTR2C (0.49) | HTR2CHTR2AHTR1DHTR6DRD3 | |
| SCHEMBL349421 | 0.74 | CYP2A6 (0.42) | — | |
| SCHEMBL31378640 | 0.74 | CYP2A6 (0.42) | — | |
| SCHEMBL13591316 | 0.73 | POLB (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |