Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952816 | 0.88 | HDAC4 (0.54) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL26546948 | 0.88 | HDAC6 (0.60) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL5457700 | 0.87 | HDAC1 (0.56) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL26614628 | 0.87 | HDAC1 (0.56) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL5333743 | 0.84 | HDAC4 (0.57) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL5333748 | 0.84 | HDAC4 (0.57) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL28528489 | 0.83 | HDAC6 (0.58) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL21241793 | 0.81 | HDAC6 (0.57) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL21241915 | 0.81 | HDAC6 (0.57) | HDAC6HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL21224416 | 0.81 | HDAC6 (0.46) | HDAC6HDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |