Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.58 |
| ▸ | SCD | O00767 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241915 | 0.92 | HDAC6 (0.57) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21241793 | 0.92 | HDAC6 (0.57) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21224173 | 0.92 | HDAC6 (0.62) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21224170 | 0.88 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21224166 | 0.88 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21241784 | 0.86 | SCD (0.58) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21241916 | 0.86 | SCD (0.58) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL23705489 | 0.84 | HDAC6 (0.76) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL28529768 | 0.84 | HDAC6 (0.76) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21224489 | 0.84 | SCD (0.60) | HDAC6HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112153984-A | Compound and use thereof | 福宏治疗公司 | 2020-12-29 | — | — | CN | disclosed |