Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 20/20 | 1.00 |
| ▸ | TYK2 | P29597 | 20/20 | 1.00 |
| ▸ | JAK2 | O60674 | 19/20 | 1.00 |
| ▸ | JAK3 | P52333 | 14/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21242564 | 1.00 | JAK1 (1.00) | JAK1TYK2JAK2JAK3CYP2C19 | |
| SCHEMBL21242552 | 1.00 | JAK1 (1.00) | JAK1TYK2JAK2JAK3CYP2C19 | |
| SCHEMBL23080443 | 1.00 | JAK1 (1.00) | JAK1TYK2JAK2JAK3CYP2C19 | |
| SCHEMBL21242553 | 0.86 | JAK2 (1.00) | JAK1TYK2JAK2JAK3CYP2C19 | |
| SCHEMBL21242580 | 0.84 | JAK1 (0.73) | JAK1TYK2JAK2JAK3CYP2C19 | |
| SCHEMBL21757000 | 0.81 | JAK2 (1.00) | JAK1TYK2JAK2JAK3CYP2C19 | |
| SCHEMBL21757090 | 0.81 | JAK2 (1.00) | JAK1TYK2JAK2JAK3CYP2C19 | |
| SCHEMBL21757111 | 0.81 | JAK2 (1.00) | JAK1TYK2JAK2JAK3CYP2C19 | |
| SCHEMBL21242556 | 0.81 | JAK2 (0.76) | JAK1TYK2JAK2JAK3CYP2C19 | |
| SCHEMBL21242963 | 0.80 | JAK1 (0.67) | JAK1TYK2JAK2JAK3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070754-A1 | JAK INHIBITOR AND USE THEREOF | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2021-03-11 | — | — | US | disclosed |
| WO-2019149244-A1 | JAK INHIBITOR AND USE THEREOF | 南京明德新药研发股份有限公司 | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070754-A1 | JAK INHIBITOR AND USE THEREOF | JAK1, JAK2, TYK2 | JAK1 1/4885TYK2 3/4885JAK2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.