SCHEMBL2124264

SCHEMBL2124264

Brc1ccc(Br)c2[nH]ccc12

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.48
PRKCI P41743 1/20 0.45
PARP1 P09874 1/20 0.43
DRD4 P21917 2/20 0.42
DRD3 P35462 2/20 0.42
DRD2 P14416 1/20 0.41
CCR8 P51685 1/20 0.37
KMT2A Q03164 1/20 0.36
DYRK1A Q13627 1/20 0.35
RHEB Q15382 1/20 0.32
PIM3 Q86V86 1/20 0.32
CFB P00751 1/20 0.31
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556631 1.00 AHR (0.48) AHRPRKCIPARP1DRD4DRD3
SCHEMBL31488003 0.81 AHR (0.42) AHRPRKCIPARP1DRD4DRD3
SCHEMBL265821 0.81 AHR (0.42) AHRPRKCIPARP1DRD4DRD3
SCHEMBL31146936 0.81 AHR (0.42) AHRPRKCIPARP1DRD4DRD3
SCHEMBL265955 0.81 AHR (0.42) AHRPRKCIPARP1DRD4DRD3
SCHEMBL25407907 0.81 DRD4 (0.39) AHRPRKCIPARP1DRD4DRD3
SCHEMBL2767894 0.81 DRD4 (0.41) AHRPRKCIPARP1DRD4DRD3
SCHEMBL620047 0.81 TNF (0.39) AHRPRKCIPARP1DRD4DRD3
SCHEMBL2768928 0.81 DRD4 (0.39) AHRPRKCIPARP1DRD4DRD3
SCHEMBL3068349 0.81 AHR (0.42) AHRPRKCIPARP1DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250063947-A1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC DEVICES HELIATEK GMBH (DE) 2025-02-20 US disclosed
EP-4024489-B1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC COMPONENTS HELIATEK GMBH (DE) 2023-10-04 EP disclosed
EP-4024489-B1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC COMPONENTS HELIATEK GMBH (DE) 2023-10-04 EP disclosed
WO-2023126486-A1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC DEVICES HELIATEK GMBH (DE) 2023-07-06 WO disclosed
WO-2023126486-A1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC DEVICES HELIATEK GMBH (DE) 2023-07-06 WO disclosed
US-20230192645-A1 INDOLE CARBOXAMIDE COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2023-06-22 US disclosed
US-20230192645-A1 INDOLE CARBOXAMIDE COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2023-06-22 US disclosed
US-11623921-B2 Indole carboxamide compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2023-04-11 US disclosed
EP-4024489-A1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC COMPONENTS Heliatek GmbH (DE) 2022-07-06 EP disclosed
EP-4024489-A1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC COMPONENTS Heliatek GmbH (DE) 2022-07-06 EP disclosed
EP-2443111-A1 1,2,4-OXADIAZOL DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS SPHINGOSINE 1-PHOSPHATE 1 RECEPTOR AGONISTS Glaxo Group Limited (GB) 2012-04-25 EP disclosed
WO-2012021591-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2012-02-16 WO disclosed
WO-2011159857-A1 CARBOLINE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2011-12-22 WO disclosed
WO-2011159857-A1 CARBOLINE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2011-12-22 WO disclosed
WO-2010145203-A1 1,2,4-OXADIAZOL DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS SPHINGOSINE 1-PHOSPHATE 1 RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2010-12-23 WO disclosed
WO-2010145203-A1 1,2,4-OXADIAZOL DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS SPHINGOSINE 1-PHOSPHATE 1 RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2010-12-23 WO disclosed
US-20100144726-A1 NOVEL INDOLIC DERIVATIVES, THEIR PREPARATION PROCESSES AND THEIR USES IN PARTICULAR AS ANTIBACTERIALS UNIVERSITE JOSEPH FOURIER (FR) 2010-06-10 US disclosed
CN-101652346-A Novel indole derivatives, process for their preparation and their use, especially as antibacterial agents UNIV JOSEPH FOURIER FR 2010-02-17 CN disclosed
EP-2121601-A2 NOVEL INDOLE DERIVATIVES, METHODS FOR PREPARING SAME, AND USE THEREOF PARTICULARLY AS ANTIBACTERIAL AGENTS Université Joseph Fourier (FR) 2009-11-25 EP disclosed
WO-2008110690-A2 NOVEL INDOLE DERIVATIVES, METHODS FOR PREPARING SAME, AND USE THEREOF PARTICULARLY AS ANTIBACTERIAL AGENTS UNIVERSITE JOSEPH FOURIER (FR) 2008-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192645-A1 INDOLE CARBOXAMIDE COMPOUNDS BTK, JAK2, BRD4 AHR 1570/4885PRKCI 531/4885PARP1 542/4885
US-11623921-B2 Indole carboxamide compounds BTK, JAK2, BRD4 AHR 1570/4885PRKCI 531/4885PARP1 542/4885
US-20250063947-A1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC DEVICES CYP2C19, CYP2C9, CYP2E1 AHR 1598/4885PRKCI 4487/4885PARP1 3132/4885
US-20100144726-A1 NOVEL INDOLIC DERIVATIVES, THEIR PREPARATION PROCESSES AND THEIR USES IN PARTICULAR AS ANTIBACTERIALS GPBAR1, TPH1, GPER1 AHR 354/4885PRKCI 2826/4885PARP1 2303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.