Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | APEX1 | P27695 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 6/20 | 0.47 |
| ▸ | HRH2 | P25021 | 3/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13779893 | 0.82 | HRH3 (0.63) | HRH3HRH4ALDH1A1MEN1GLA | |
| Histidinol SCHEMBL6546332 | 0.81 | HRH4 (0.61) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL6546327 | 0.81 | HRH4 (0.61) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL4506698 | 0.81 | HRH3 (0.61) | HRH3HRH4ALDH1A1MEN1GLA | |
| Histidinol SCHEMBL407337 | 0.81 | HRH4 (0.61) | HRH3HRH4ALDH1A1MEN1GLA | |
| Histidinol SCHEMBL10002446 | 0.81 | HRH4 (0.61) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL13436837 | 0.80 | — | — | |
| Histidinol SCHEMBL29986891 | 0.79 | HRH4 (0.62) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL12328968 | 0.76 | — | — | |
| SCHEMBL3925179 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758426-B1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK AS (DK) | 2019-08-07 | — | — | EP | disclosed |