Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099674 | 1.00 | GLP1R (0.49) | GLP1RKDM4EADRA1AEPHX2TSHR | |
| SCHEMBL24227214 | 0.96 | GLP1R (0.51) | GLP1RKDM4EADRA1AEPHX2TSHR | |
| SCHEMBL21242757 | 0.95 | GLP1R (0.49) | GLP1RKDM4EADRA1AEPHX2TSHR | |
| SCHEMBL8234605 | 0.95 | GLP1R (0.49) | GLP1RKDM4EADRA1AEPHX2TSHR | |
| SCHEMBL21242727 | 0.92 | GLP1R (0.48) | GLP1RKDM4EADRA1AEPHX2TSHR | |
| SCHEMBL12673887 | 0.92 | GLP1R (0.48) | GLP1RKDM4EADRA1AEPHX2TSHR | |
| SCHEMBL15107521 | 0.92 | GLP1R (0.48) | GLP1RKDM4EADRA1AEPHX2TSHR | |
| SCHEMBL8237352 | 0.92 | GLP1R (0.48) | GLP1RKDM4EADRA1AEPHX2TSHR | |
| SCHEMBL19645170 | 0.92 | ADRA1A (0.53) | GLP1RADRA1AEPHX2PRMT1ITGB3 | |
| SCHEMBL15259303 | 0.91 | GLP1R (0.48) | GLP1RKDM4EADRA1AEPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758426-B1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK AS (DK) | 2019-08-07 | — | — | EP | disclosed |