Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656982 | 0.85 | PTPN1 (0.89) | PTPN1HPGDNPSR1RAB9ALMNA | |
| SCHEMBL125695 | 0.85 | PTPN1 (0.89) | PTPN1HPGDNPSR1RAB9ALMNA | |
| SCHEMBL19185753 | 0.85 | GAA (0.68) | PTPN1HPGDNPSR1RAB9ALMNA | |
| SCHEMBL12545585 | 0.83 | PTPN1 (0.68) | PTPN1HPGDNPSR1RAB9ALMNA | |
| SCHEMBL25647118 | 0.83 | PTPN1 (0.68) | PTPN1HPGDNPSR1RAB9ALMNA | |
| SCHEMBL12975171 | 0.81 | GAA (0.72) | PTPN1HPGDNPSR1RAB9ALMNA | |
| SCHEMBL24645052 | 0.79 | NPSR1 (0.69) | PTPN1NPSR1RAB9ALMNANAMPT | |
| SCHEMBL9198985 | 0.79 | PTPN1 (0.71) | PTPN1HPGDNPSR1RAB9ALMNA | |
| SCHEMBL62827 | 0.79 | PTPN1 (0.71) | PTPN1HPGDNPSR1RAB9ALMNA | |
| SCHEMBL4448787 | 0.79 | PTPN1 (0.71) | PTPN1HPGDNPSR1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3049388-B1 | NUCLEATING AGENT FOR THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & CO (US) | 2019-08-07 | — | — | EP | disclosed |