Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25298953 | 0.96 | RAB9A (0.70) | PTPN1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL9342656 | 0.92 | KMT2A (0.72) | PTPN1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL125695 | 0.88 | PTPN1 (0.89) | PTPN1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL28656982 | 0.88 | PTPN1 (0.89) | PTPN1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL17730000 | 0.86 | KMT2A (0.64) | PTPN1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL18395563 | 0.84 | KMT2A (0.58) | PTPN1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL13972924 | 0.84 | KMT2A (0.62) | PTPN1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL13552831 | 0.83 | KMT2A (0.65) | RAB9ANPC1KMT2AL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4714884 | 0.83 | KMT2A (0.56) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL23045895 | 0.83 | KMT2A (0.65) | PTPN1RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688418-B1 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARM INC (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-0661276-A1 | Herbicidal phenylsulfamoyl-pyrimidinyl ureas | BAYER AG (DE) | 1995-07-05 | — | — | EP | disclosed |