Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 8/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21242622 | 1.00 | CES2 (0.42) | CES2MEN1KMT2ATSHRRECQL | |
| SCHEMBL21242696 | 1.00 | CES2 (0.42) | CES2MEN1KMT2ATSHRRECQL | |
| SCHEMBL21440826 | 0.95 | MEN1 (0.41) | CES2MEN1KMT2ATSHRRECQL | |
| SCHEMBL19544555 | 0.95 | MEN1 (0.41) | CES2MEN1KMT2ATSHRRECQL | |
| SCHEMBL12641023 | 0.95 | MEN1 (0.41) | CES2MEN1KMT2ATSHRRECQL | |
| SCHEMBL21440855 | 0.95 | MEN1 (0.41) | CES2MEN1KMT2ATSHRRECQL | |
| SCHEMBL12118184 | 0.95 | MEN1 (0.41) | CES2MEN1KMT2ATSHRRECQL | |
| SCHEMBL13040233 | 0.92 | MEN1 (0.41) | CES2MEN1KMT2ATSHRRECQL | |
| SCHEMBL7006602 | 0.92 | MEN1 (0.41) | CES2MEN1KMT2ATSHRRECQL | |
| SCHEMBL13034764 | 0.92 | MEN1 (0.41) | CES2MEN1KMT2ATSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758426-B1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK AS (DK) | 2019-08-07 | — | — | EP | disclosed |