Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30261641 | 1.00 | ALDH1A1 (0.59) | ALDH1A1KMT2AATMAPPGAA | |
| SCHEMBL9717131 | 0.92 | ALDH1A1 (0.54) | ALDH1A1KMT2AATMAPPGAA | |
| SCHEMBL23418669 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KMT2AATMAPPGAA | |
| Inositol Niacinate SCHEMBL13557040 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KMT2AATMAPPGAA | |
| Inositol Niacinate SCHEMBL29499769 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KMT2AATMAPPGAA | |
| Inositol Niacinate SCHEMBL122590 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KMT2AATMAPPGAA | |
| Inositol Niacinate SCHEMBL122591 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KMT2AATMAPPGAA | |
| SCHEMBL31113601 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AATMGAAMAPT | |
| SCHEMBL30184905 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KMT2AATMGAAMAPT | |
| SCHEMBL20433953 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AATMAPPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180521-B2 | Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof | METRO INTERNATIONAL BIOTECH, LLC (US) | 2021-11-23 | — | — | US | disclosed |
| US-20210032280-A1 | NICOTINAMIDE RIBOSIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | METRO INTERNATIONAL BIOTECH, LLC | 2021-02-04 | — | — | US | disclosed |
| WO-2019152416-A1 | NICOTINAMIDE RIBOSIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | METRO INTERNATIONAL BIOTECH, LLC (US) | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032280-A1 | NICOTINAMIDE RIBOSIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | NAMPT, NADK, NNT | ALDH1A1 647/4885KMT2A 3784/4885ATM 1920/4885 |
| US-11180521-B2 | Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof | NAMPT, NADK, NNT | ALDH1A1 647/4885KMT2A 3784/4885ATM 1920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.