Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.84 |
| ▸ | ATM | Q13315 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502583 | 0.93 | ALDH1A1 (0.78) | KMT2AATMALDH1A1MAPTKDM4E | |
| SCHEMBL5240749 | 0.92 | KMT2A (1.00) | KMT2AATMALDH1A1MAPTKDM4E | |
| SCHEMBL9717156 | 0.92 | KMT2A (0.72) | KMT2AATMALDH1A1MAPTKDM4E | |
| SCHEMBL29603721 | 0.92 | KMT2A (1.00) | KMT2AATMALDH1A1MAPTKDM4E | |
| SCHEMBL31006272 | 0.92 | KMT2A (1.00) | KMT2AATMALDH1A1MAPTKDM4E | |
| SCHEMBL23488239 | 0.92 | KMT2A (0.72) | KMT2AATMALDH1A1MAPTKDM4E | |
| SCHEMBL23488236 | 0.90 | KMT2A (0.70) | KMT2AATMALDH1A1MAPTKDM4E | |
| SCHEMBL21963567 | 0.89 | KMT2A (0.78) | KMT2AATMALDH1A1MAPTKDM4E | |
| SCHEMBL8061344 | 0.88 | KMT2A (0.68) | KMT2AATMALDH1A1MAPTKDM4E | |
| SCHEMBL31006270 | 0.87 | KMT2A (0.69) | KMT2AATMALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180521-B2 | Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof | METRO INTERNATIONAL BIOTECH, LLC (US) | 2021-11-23 | — | — | US | disclosed |
| US-20210032280-A1 | NICOTINAMIDE RIBOSIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | METRO INTERNATIONAL BIOTECH, LLC | 2021-02-04 | — | — | US | disclosed |
| WO-2019152416-A1 | NICOTINAMIDE RIBOSIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | METRO INTERNATIONAL BIOTECH, LLC (US) | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032280-A1 | NICOTINAMIDE RIBOSIDE ANALOGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | NAMPT, NADK, NNT | KMT2A 3784/4885ATM 1920/4885ALDH1A1 647/4885 |
| US-11180521-B2 | Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof | NAMPT, NADK, NNT | KMT2A 3784/4885ATM 1920/4885ALDH1A1 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.