SCHEMBL21243890

SCHEMBL21243890

O=c1[nH]ccc2c1sc1ccsc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 6/20 0.40
PDPK1 O15530 1/20 0.40
PRKACA P17612 1/20 0.35
PRKACG P22612 1/20 0.35
PRKACB P22694 1/20 0.35
GPR35 Q9HC97 1/20 0.35
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
PARP15 Q460N3 1/20 0.33
HSD17B10 Q99714 1/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TYMP P19971 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL390375 0.75 PARP1 (0.46) PARP1PDPK1RAB9ARECQLTDP1
SCHEMBL19220745 0.74 GPR35 (0.41) GPR35
Hydrochloric Acid SCHEMBL391441 0.73 PARP1 (0.44) PARP1PDPK1RAB9ARECQLTDP1
SCHEMBL793866 0.73 TNKS (0.51) PARP1KDM4EALDH1A1LMNACYP1A2
SCHEMBL9976818 0.72 GPR35 (0.39) GPR35
SCHEMBL2435365 0.67 PARP1 (0.42) PARP1PDPK1KDM4EALDH1A1LMNA
SCHEMBL1158425 0.66 GPR35 (0.45) GPR35
SCHEMBL16706172 0.66 GPR35 (0.35) GPR35
SCHEMBL14925152 0.65 GPR35 (0.37) GPR35
SCHEMBL32691553 0.64 PARP1 (0.53) PARP1PDPK1PRKACAPRKACGPRKACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034190-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-01-30 US disclosed
US-12122794-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 US disclosed
CN-116903675-A Organic electroluminescent material and device 环球展览公司 2023-10-20 CN disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-20220041636-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-02-10 US disclosed
US-11180519-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-23 US disclosed
US-11180519-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-23 US disclosed
US-20190248818-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed
US-20190248818-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248818-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR PARP1 1758/4885PDPK1 4782/4885PRKACA 4345/4885
US-11180519-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR PARP1 1758/4885PDPK1 4782/4885PRKACA 4345/4885
US-20250034190-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR PARP1 1970/4885PDPK1 4785/4885PRKACA 4403/4885
US-20220041636-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR PARP1 1861/4885PDPK1 4751/4885PRKACA 4436/4885
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR PARP1 1946/4885PDPK1 4787/4885PRKACA 4400/4885
US-12122794-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR PARP1 1946/4885PDPK1 4787/4885PRKACA 4400/4885
US-11697662-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR PARP1 1861/4885PDPK1 4751/4885PRKACA 4436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.