SCHEMBL2124608

SCHEMBL2124608

CCCC(=O)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5857032 0.97
SCHEMBL6535348 0.83
SCHEMBL1019049 0.81
SCHEMBL30082500 0.81 MCL1 (0.33)
SCHEMBL28626065 0.79 CES2 (0.54)
SCHEMBL28312201 0.79 CES2 (0.54)
SCHEMBL9743864 0.79 CES2 (0.54)
SCHEMBL2122905 0.75
SCHEMBL2121575 0.75 CES2 (0.50)
SCHEMBL13799020 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10202345-B2 Substituted azaspiro(4.5)decane derivatives GRUENENTHAL GMBH (DE) 2019-02-12 US claimed
EP-0417555-B1 Pentamethine dyes and derivatives BAYER AG (DE) 1993-11-03 EP claimed
US-5118814-A Pressure sensitive and heat sensitive recording media BAYER AKTIENGESELLSCHAFT (DE) 1992-06-02 US claimed
EP-0417555-A1 Pentamethine dyes and derivatives BAYER AG (DE) 1991-03-20 EP claimed
EP-0370198-A1 Tetraindolyl heptamethine derivatives BAYER AG (DE) 1990-05-30 EP claimed
EP-0010179-B1 PROCESS FOR THE PREPARATION OF 2.2-DIALKYLPENTANE-1.5-DIAMINES, AND THE COMPOUNDS N-(4-CYANO-2.2-DIETHYLBUTYL)-4-CYANO-2.2-DIMETHYL BUTYLIDENE IMINE AND N-(4-CYANO-2-N-BUTYL-2-ETHYLBUTYL)-4-CYANO-2-N-BUTYL-2-ETHYL-BUTYLIDENE IMINE Ruhrchemie Aktiengesellschaft (DE) 1982-05-19 EP claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US disclosed
CN-118812519-A Substituted tetrahydrofurans as Nav1.8 inhibitors 武汉人福创新药物研发中心有限公司 2024-10-22 CN disclosed
CN-113614079-A Crystals of heterocyclic amide compound and process for producing the same 日产化学株式会社 2021-11-05 CN disclosed
WO-2021049932-A1 PHOTO BIOCATALYTIC SYNTHESIS OF SECONDARY FATTY ALCOHOLS FROM UNSATURATED FATTY ACIDS TECHNISCHE UNIVERSITEIT DELFT (NL) 2021-03-18 WO disclosed
CN-107428702-A Improved process for preparing statin precursors 中化帝斯曼制药有限公司荷兰公司 2017-12-01 CN disclosed
WO-2017060873-A1 SUBSTITUTED PYRAZOLO[3,4-B]PYRIDIN-6-CARBOXYLIC ACIDS AND THEIR USE AbbVie S.à.r.l. (LU) 2017-04-13 WO disclosed
US-20170012072-A1 INFRARED SENSOR, NEAR-INFRARED ABSORBING COMPOSITION, CURED FILM, NEAR-INFRARED ABSORBING FILTER, IMAGE SENSOR, CAMERA MODULE, AND COMPOUND FUJIFILM CORPORATION (JP) 2017-01-12 US disclosed
EP-0417555-B1 Pentamethine dyes and derivatives BAYER AG (DE) 1993-11-03 EP disclosed
US-5138070-A Laser transfer printing; opticalrecording media BAYER AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
US-5118814-A Pressure sensitive and heat sensitive recording media BAYER AKTIENGESELLSCHAFT (DE) 1992-06-02 US disclosed
EP-0370198-A1 Tetraindolyl heptamethine derivatives BAYER AG (DE) 1990-05-30 EP disclosed
EP-0093338-A1 Method for the preparation of cyanohydrine-carboxylic-acid esters BAYER AG (DE) 1983-11-09 EP disclosed
EP-0010179-A1 Process for the preparation of 2.2-dialkylpentane-1.5-diamines, and the compounds N-(4-cyano-2.2-diethylbutyl)-4-cyano-2.2-dimethyl butylidene imine and N-(4-cyano-2-n-butyl-2-ethylbutyl)-4-cyano-2-n-butyl-2-ethyl-butylidene imine Ruhrchemie Aktiengesellschaft (DE) 1980-04-30 EP disclosed
US-4161491-A Process for the production of alpha-ketocarboxylic acid amides and cycloaliphatic products DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-07-17 US disclosed