⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569966 | 0.81 | PTAFR (0.45) | — | |
| SCHEMBL28047584 | 0.79 | PTAFR (0.31) | — | |
| SCHEMBL24312336 | 0.75 | LGALS8 (0.32) | — | |
| SCHEMBL25611163 | 0.75 | — | — | |
| SCHEMBL31493145 | 0.75 | — | — | |
| SCHEMBL6936580 | 0.72 | PTAFR (0.46) | — | |
| SCHEMBL9680769 | 0.71 | — | — | |
| SCHEMBL9679837 | 0.71 | — | — | |
| SCHEMBL9680776 | 0.71 | — | — | |
| SCHEMBL9679842 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11071789-B2 | Pharmaceutical prodrugs and methods of their preparation and use | CEPHALON, INC. (US) | 2021-07-27 | — | — | US | disclosed |
| US-20190240348-A1 | PHARMACEUTICAL PRODRUGS AND METHODS OF THEIR PREPARATION AND USE | CEPHALON, INC. (US) | 2019-08-08 | — | — | US | disclosed |