Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | MARK3 | P27448 | 1/20 | 0.48 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1196430 | 0.84 | L3MBTL1 (0.59) | L3MBTL1EPHX1MEN1KMT2APIM1 | |
| SCHEMBL1196432 | 0.84 | L3MBTL1 (0.62) | L3MBTL1EPHX1MEN1KMT2APIM1 | |
| SCHEMBL21259294 | 0.84 | L3MBTL1 (0.59) | L3MBTL1EPHX1MEN1KMT2APIM1 | |
| SCHEMBL21259416 | 0.83 | L3MBTL1 (0.57) | L3MBTL1EPHX1MEN1KMT2APIM1 | |
| SCHEMBL15853328 | 0.83 | L3MBTL1 (0.57) | L3MBTL1EPHX1MEN1KMT2APIM1 | |
| SCHEMBL10819499 | 0.83 | L3MBTL1 (0.57) | L3MBTL1EPHX1MEN1KMT2APIM1 | |
| SCHEMBL29651127 | 0.83 | L3MBTL1 (0.57) | L3MBTL1EPHX1MEN1KMT2APIM1 | |
| SCHEMBL14222808 | 0.83 | L3MBTL1 (0.57) | L3MBTL1EPHX1MEN1KMT2APIM1 | |
| SCHEMBL1055676 | 0.83 | L3MBTL1 (0.57) | L3MBTL1EPHX1MEN1KMT2APIM1 | |
| SCHEMBL20033885 | 0.83 | L3MBTL1 (0.57) | L3MBTL1EPHX1MEN1KMT2APIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785103-A | Synthetic method of medicine fubatinib for treating bile duct cancer | 北京康立生医药技术开发有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-108299279-B | Substituted arylaminol compounds, methods of making, and uses thereof | 北京梅尔森医药技术开发有限公司 | 2021-03-23 | — | — | CN | disclosed |
| WO-2019153216-A1 | SUBSTITUTED ARYLAMINO ALCOHOL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 北京梅尔森医药技术开发有限公司 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153216-A1 | SUBSTITUTED ARYLAMINO ALCOHOL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 北京梅尔森医药技术开发有限公司 | 2019-08-15 | — | — | WO | disclosed |
| CN-108299279-A | Substituted aryl amine alcohol compound and its preparation method and application | 北京梅尔森医药技术开发有限公司 | 2018-07-20 | — | — | CN | disclosed |