Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.51 |
| ▸ | HRH1 | P35367 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | HRH2 | P25021 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21542538 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CHRM2ADRA2B | |
| SCHEMBL29637254 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CHRM2ADRA2B | |
| SCHEMBL29637255 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CHRM2ADRA2B | |
| SCHEMBL29637252 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CHRM2ADRA2B | |
| SCHEMBL3678911 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CHRM2ADRA2B | |
| SCHEMBL23421389 | 0.84 | KMT2A (0.53) | SLC6A2SLC6A4SLC6A3CHRM2ADRA2B | |
| SCHEMBL31143646 | 0.84 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CHRM2CYP2D6 | |
| SCHEMBL31143614 | 0.84 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CHRM2CYP2D6 | |
| SCHEMBL477369 | 0.84 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CHRM2CYP2D6 | |
| SCHEMBL23610057 | 0.84 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CHRM2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164419-A | Chiral synthesis method of bestatin intermediate | 江苏联环药业股份有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-115992127-A | Alcohol dehydrogenation/reductase phosphate hybridization nanoflower and preparation method and application thereof | 浙江工业大学 | 2023-04-21 | — | — | CN | claimed |
| CN-102559520-B | Method for preparing (S)-(4-chlorphenyl)-(pyridine-2-yl)-methanol by utilizing microbial catalysis | UNIV JIANGNAN | 2013-11-20 | — | — | CN | claimed |
| CN-102675283-B | Method for preparing bepotastine by condensation under acidic condition | SHANGHAI YOUSHOU PHARMACEUTICAL TECHNOLOGY DEV CO LTD | 2013-08-14 | — | — | CN | claimed |
| CN-102675283-A | New method for preparing bepotastine by condensation under acidic condition | SHANGHAI YOUSHOU MEDICAL TECHNOLOGY DEV CO LTD | 2012-09-19 | — | — | CN | claimed |
| CN-102559520-A | Method for preparing (S)-(4-chlorphenyl)-(pyridine-2-yl)-methanol by utilizing microbial catalysis | UNIV JIANGNAN | 2012-07-11 | — | — | CN | claimed |
| CN-113480521-B | Full synthesis method of bepotastine besilate | 成都丽凯手性技术有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117164419-A | Chiral synthesis method of bestatin intermediate | 江苏联环药业股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117164419-A | Chiral synthesis method of bestatin intermediate | 江苏联环药业股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-115992127-A | Alcohol dehydrogenation/reductase phosphate hybridization nanoflower and preparation method and application thereof | 浙江工业大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115992127-A | Alcohol dehydrogenation/reductase phosphate hybridization nanoflower and preparation method and application thereof | 浙江工业大学 | 2023-04-21 | — | — | CN | disclosed |
| US-11542479-B2 | Alcohol dehydrogenase mutant and use thereof | JIANGNAN UNIVERSITY (CN) | 2023-01-03 | — | — | US | disclosed |
| US-11542479-B2 | Alcohol dehydrogenase mutant and use thereof | JIANGNAN UNIVERSITY (CN) | 2023-01-03 | — | — | US | disclosed |
| CN-102559520-B | Method for preparing (S)-(4-chlorphenyl)-(pyridine-2-yl)-methanol by utilizing microbial catalysis | UNIV JIANGNAN | 2013-11-20 | — | — | CN | disclosed |
| CN-102559520-B | Method for preparing (S)-(4-chlorphenyl)-(pyridine-2-yl)-methanol by utilizing microbial catalysis | UNIV JIANGNAN | 2013-11-20 | — | — | CN | disclosed |
| CN-102559520-B | Method for preparing (S)-(4-chlorphenyl)-(pyridine-2-yl)-methanol by utilizing microbial catalysis | UNIV JIANGNAN | 2013-11-20 | — | — | CN | disclosed |
| CN-103121966-A | Method for directionally synthesizing (4-chlorphenyl)-(pyridine-2-base)-methanol | CHONGQING HUABANG SHENGKAI PHARMACEUTICAL CO LTD | 2013-05-29 | — | — | CN | disclosed |
| CN-102559520-A | Method for preparing (S)-(4-chlorphenyl)-(pyridine-2-yl)-methanol by utilizing microbial catalysis | UNIV JIANGNAN | 2012-07-11 | — | — | CN | disclosed |
| CN-102559520-A | Method for preparing (S)-(4-chlorphenyl)-(pyridine-2-yl)-methanol by utilizing microbial catalysis | UNIV JIANGNAN | 2012-07-11 | — | — | CN | disclosed |
| CN-102559520-A | Method for preparing (S)-(4-chlorphenyl)-(pyridine-2-yl)-methanol by utilizing microbial catalysis | UNIV JIANGNAN | 2012-07-11 | — | — | CN | disclosed |