SCHEMBL477369

SCHEMBL477369

OC(c1ccccc1)c1ccccn1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.63
SLC6A4 P31645 2/20 0.63
SLC6A3 Q01959 1/20 0.63
KDM4E B2RXH2 4/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP1A2 P05177 1/20 0.50
MAPT P10636 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
SLC10A1 Q14973 1/20 0.47
CHRM2 P08172 1/20 0.47
SCN1A P35498 1/20 0.47
SCN2A Q99250 1/20 0.47
SCN3A Q9NY46 1/20 0.47
LMNA P02545 2/20 0.46
CYP2D6 P10635 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
BRD4 O60885 1/20 0.43
RECQL P46063 1/20 0.43
OPRM1 P35372 1/20 0.43
OPRD1 P41143 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31143614 1.00 SLC6A2 (0.63) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL31143646 1.00 SLC6A2 (0.63) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL23610057 1.00 SLC6A2 (0.63) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL23882742 0.88 CYP3A4 (0.49) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL23882741 0.88 CYP3A4 (0.49) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL3048607 0.86 MAPT (0.55) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL29864658 0.86 MAPT (0.55) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL15709920 0.86 AHR (0.54) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL23610040 0.84 BRD4 (0.49) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL21542538 0.84 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104328154-A Method for producing (S)-phenyl methanol from blue mold UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-02-04 CN claimed
EP-1296952-B9 BENZOYLPYRIDINE DERIVATIVE OR ITS SALT, FUNGICIDE CONTAINING IT AS AN ACTIVE INGREDIENT, ITS PRODUCTION PROCESS AND INTERMEDIATE FOR PRODUCING IT ISHIHARA SANGYO KAISHA (JP) 2008-01-09 EP claimed
EP-1296952-B1 BENZOYLPYRIDINE DERIVATIVE OR ITS SALT, FUNGICIDE CONTAINING IT AS AN ACTIVE INGREDIENT, ITS PRODUCTION PROCESS AND INTERMEDIATE FOR PRODUCING IT ISHIHARA SANGYO KAISHA (JP) 2007-09-12 EP claimed
CN-100336807-C Benzoylpyridine derivative or its salt, fungicide containing it as active ingredient, its production method and intermediate for producing it ISHIHARA SANGYO KAISHA (JP) 2007-09-12 CN claimed
CN-1907969-A Benzoylpyridine derivative or its salt, disinfectant containing the same as active ingredient method for producing the same and intermediate for producing the same ISHIHARA SANGYO KAISHA (JP) 2007-02-07 CN claimed
US-20060089390-A1 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-04-27 US claimed
EP-1559320-A1 3-BENZOYL-2,4,5-SUBSTITUTED PYRIDINE DERIVATIVES OR SALTS THEREOF AND BACTERICIDES CONTAINING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2005-08-03 EP claimed
US-6770662-B2 PLANT DISEASES; POWDERY MILDEW OF BARLEY, VEGETABLES, FRUITS AND FLOWERING PLANTS ISHIHARA SANGYO KAISHA, LTD. (JP) 2004-08-03 US claimed
US-20030216444-A1 Benzoylpyridine derivative or its salt, fungicide containing it as an active ingredient, its production process and intermediate for producing it ISHIHARA SANGYO KAISHA, LTD. (JP) 2003-11-20 US claimed
CN-1440389-A Benzoylpyridine derivative or its salt, fungicide containing it as active ingredient, its production method and intermediate for producing it ISHIHARA SANGYO KAISHA (JP) 2003-09-03 CN claimed
EP-1296952-A1 BENZOYLPYRIDINE DERIVATIVE OR ITS SALT, FUNGICIDE CONTAINING IT AS AN ACTIVE INGREDIENT, ITS PRODUCTION PROCESS AND INTERMEDIATE FOR PRODUCING IT ISHIHARA SANGYO KAISHA, LTD. (JP) 2003-04-02 EP claimed
WO-2002002527-A1 BENZOYLPYRIDINE DERIVATIVE OR ITS SALT, FUNGICIDE CONTAINING IT AS AN ACTIVE INGREDIENT, ITS PRODUCTION PROCESS AND INTERMEDIATE FOR PRODUCING IT ISHIHARA SANGYO KAISHA, LTD. (JP) 2002-01-10 WO claimed
US-5969166-A RUTHENIUM OR MOLYBDENUM CATALYSTS FOR EPOXIDATION OF ALKENES WITH OXYGEN HOECHST AKTIENGESELLSCHAFT (DE) 1999-10-19 US claimed
EP-0869843-A1 EPOXIDES PRODUCED BY THE OXIDATION OF OLEFINES WITH AIR OR OXYGEN HOECHST AKTIENGESELLSCHAFT (DE) 1998-10-14 EP claimed
WO-1996020788-A1 EPOXIDES PRODUCED BY THE OXIDATION OF OLEFINES WITH AIR OR OXYGEN HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-11 WO claimed
EP-0686635-A1 Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1995-12-13 EP claimed
US-5470851-A Antihistamine, anticoagulants SANKYO COMPANY, LIMITED (JP) 1995-11-28 US claimed
EP-0549364-A1 Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1993-06-30 EP claimed
JP-64003170-A None JP disclosed
EP-0069521-A2 Pyridinyl and imidazolyl derivatives of benzofurans and benzothiophenes THE UPJOHN COMPANY (US) 1983-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216444-A1 Benzoylpyridine derivative or its salt, fungicide containing it as an active ingredient, its production process and intermediate for producing it CBR1, KCNH1, CBR3 SLC6A2 1042/4885SLC6A4 1180/4885SLC6A3 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.