Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247271 | 0.88 | PTPN1 (0.55) | ALDH1A1HPGDLMNAKDM4ETP53 | |
| SCHEMBL21247402 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL21247102 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL21247182 | 0.84 | MAPT (0.63) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL22655231 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL21247158 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL21247242 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL21247247 | 0.77 | PTPN1 (0.53) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL21261014 | 0.77 | PTPN1 (0.50) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL21247169 | 0.76 | PTPN1 (0.53) | ALDH1A1HPGDLMNAKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749659-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO Pharma (FR) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154950-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |