Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935310 | 0.86 | MEN1 (0.47) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL4147783 | 0.86 | ESRRG (0.49) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL2881402 | 0.86 | PPARA (0.49) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL1027884 | 0.86 | MEN1 (0.47) | KMT2AMEN1HTTL3MBTL1TAAR1 | |
| SCHEMBL1845384 | 0.84 | MEN1 (0.46) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL11898599 | 0.84 | MEN1 (0.46) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL21997106 | 0.84 | KMT2A (0.46) | KMT2AMEN1HTTL3MBTL1TAAR1 | |
| SCHEMBL1935745 | 0.84 | MEN1 (0.46) | KMT2AMEN1HTTL3MBTL1TAAR1 | |
| SCHEMBL19921435 | 0.84 | CYP2C9 (0.49) | KMT2AMEN1HTTL3MBTL1LMNA | |
| SCHEMBL2575721 | 0.84 | TAAR1 (0.50) | KMT2AMEN1HTTL3MBTL1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154329-A1 | COMPOUND HAVING BET INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREFOR | 上海海和药物研究开发有限公司 | 2019-08-15 | — | — | WO | disclosed |