Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935310 | 0.90 | MEN1 (0.47) | PPARAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL2882037 | 0.89 | PPARA (0.45) | PPARAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL4147783 | 0.86 | ESRRG (0.49) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL1027884 | 0.86 | MEN1 (0.47) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL21247482 | 0.86 | KMT2A (0.63) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL11898599 | 0.85 | MEN1 (0.46) | PPARAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL2575721 | 0.85 | TAAR1 (0.50) | PPARAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL21997106 | 0.85 | KMT2A (0.46) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL1845384 | 0.85 | MEN1 (0.46) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL1935745 | 0.85 | MEN1 (0.46) | PPARAMEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | MSD K.K. (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | NPY1R, MC5R, MC1R | PPARA 1244/4885MEN1 375/4885KMT2A 1658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.