Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 18/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21249507 | 0.86 | APLNR (0.49) | APLNR | |
| SCHEMBL21229196 | 0.86 | APLNR (0.65) | APLNRNTSR1OPRM1OPRD1 | |
| SCHEMBL17326464 | 0.86 | APLNR (0.65) | APLNRNTSR1OPRM1OPRD1 | |
| SCHEMBL17326466 | 0.86 | APLNR (0.49) | APLNR | |
| SCHEMBL21468240 | 0.82 | APLNR (0.49) | APLNR | |
| SCHEMBL17326455 | 0.80 | APLNR (0.59) | APLNR | |
| SCHEMBL21468236 | 0.80 | APLNR (0.52) | APLNRNTSR1OPRM1OPRD1 | |
| SCHEMBL21249643 | 0.80 | APLNR (0.60) | APLNR | |
| SCHEMBL17326451 | 0.80 | APLNR (0.57) | APLNR | |
| SCHEMBL17326315 | 0.78 | APLNR (0.49) | APLNRNTSR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377718-B2 | Apelin receptor (APJ) agonists and uses thereof | RESEARCH TRIANGLE INSTITUTE (US) | 2019-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377718-B2 | Apelin receptor (APJ) agonists and uses thereof | APLNR, AP1G1, APMAP | APLNR 1/4885NTSR1 15/4885OPRM1 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.