Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 2/20 | 0.41 |
| ▸ | EEF2 | P13639 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5291587 | 0.87 | MEN1 (0.49) | PON1EEF2KEEF2MEN1KMT2A | |
| SCHEMBL1076866 | 0.86 | KMT2A (0.42) | MEN1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL9661522 | 0.85 | MEN1 (0.47) | PON1EEF2KEEF2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9664604 | 0.85 | MEN1 (0.47) | PON1EEF2KEEF2MEN1KMT2A | |
| SCHEMBL5304274 | 0.85 | KDM4E (0.40) | PON1EEF2KEEF2MEN1KMT2A | |
| Iodide SCHEMBL9160116 | 0.84 | KMT2A (0.41) | MEN1KMT2ACA1CA2 | |
| Bromide SCHEMBL1077950 | 0.84 | KMT2A (0.43) | MEN1KMT2ACA1CA2 | |
| SCHEMBL27681815 | 0.84 | KMT2A (0.41) | PON1MEN1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL23698411 | 0.84 | PON1 (0.41) | PON1EEF2KEEF2MEN1KMT2A | |
| Bromide SCHEMBL15817933 | 0.84 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10378046-B2 | Method of targeting mismatched DNA using d8 square planar metal complexes | THE UNIVERSITY OF HONG KONG (CN) | 2019-08-13 | — | — | US | disclosed |