Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 14/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10193849 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1MAPK1LMNA | |
| SCHEMBL18936072 | 0.80 | NAMPT (0.40) | TDP1MAPK1NAMPT | |
| SCHEMBL15185945 | 0.79 | NAMPT (0.35) | TSHRNAMPTALOX15 | |
| SCHEMBL16288468 | 0.79 | NAMPT (0.35) | TSHRNAMPTALOX15 | |
| SCHEMBL16287230 | 0.79 | NAMPT (0.35) | TSHRNAMPTALOX15 | |
| SCHEMBL15185941 | 0.79 | NAMPT (0.35) | TSHRNAMPTALOX15 | |
| SCHEMBL10729681 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1MAPK1LMNA | |
| SCHEMBL368411 | 0.79 | — | — | |
| SCHEMBL16288859 | 0.78 | NAMPT (0.36) | ALDH1A1TSHRLMNANAMPTALOX15 | |
| SCHEMBL15185946 | 0.78 | NAMPT (0.36) | ALDH1A1TSHRLMNANAMPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524603-A1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |