Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108582 | 0.90 | P2RX7 (0.86) | P2RX7 | |
| SCHEMBL21253383 | 0.84 | P2RX7 (0.62) | P2RX7 | |
| SCHEMBL107414 | 0.83 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL9930930 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL21253359 | 0.82 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL9931417 | 0.82 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL21253520 | 0.82 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL21253554 | 0.82 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL21253574 | 0.82 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL21253578 | 0.82 | P2RX7 (0.70) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191488-B1 | P2X7 MODULATING N-ACYL-TRIAZOLOPYRAZINES | JANSSEN PHARMACEUTICA NV (BE) | 2019-08-14 | — | — | EP | disclosed |