Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559843 | 0.92 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL27423567 | 0.90 | POLB (0.38) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL21254293 | 0.90 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL22360394 | 0.90 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL21087449 | 0.89 | POLB (0.35) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL18468447 | 0.88 | POLB (0.38) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL19159130 | 0.88 | POLB (0.32) | POLBAPEX1HTTTDP1RARA | |
| SCHEMBL16559855 | 0.88 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL16559858 | 0.88 | POLB (0.43) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL22845982 | 0.87 | TDP1 (0.37) | POLBAPEX1HTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230007940-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCKP PATENT GMBH (DE) | 2023-01-12 | — | — | US | disclosed |
| EP-4001378-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2022-05-25 | — | — | EP | disclosed |
| EP-3521401-B1 | COMPOUNDS FOR HOMEOTROPIC ALIGNMENT OF LIQUID CRYSTALINE MEDIA | MERCK PATENT GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |
| EP-3730591-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3246374-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-08-14 | — | — | EP | disclosed |