Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19159169 | 0.96 | POLB (0.38) | POLBAPEX1HTTTDP1NR4A2 | |
| SCHEMBL16559843 | 0.96 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL16559858 | 0.92 | POLB (0.43) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL16559855 | 0.92 | POLB (0.40) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL24555444 | 0.90 | POLB (0.44) | POLBAPEX1HTTTDP1CHEK2 | |
| SCHEMBL26044722 | 0.90 | POLB (0.44) | POLBAPEX1HTTTDP1CHEK2 | |
| SCHEMBL19824585 | 0.90 | POLB (0.44) | POLBAPEX1HTTTDP1CHEK2 | |
| SCHEMBL19159179 | 0.89 | POLB (0.36) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL25795454 | 0.89 | POLB (0.36) | POLBAPEX1HTTTDP1PTGS2 | |
| SCHEMBL24355952 | 0.89 | POLB (0.37) | POLBAPEX1HTTTDP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306614-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2024-01-17 | — | — | EP | disclosed |
| EP-3628721-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-3127989-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| EP-3127989-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2017-02-08 | — | — | EP | disclosed |