Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.79 |
| ▸ | MAOA | P21397 | 2/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.79 |
| ▸ | DRD1 | P21728 | 6/20 | 0.65 |
| ▸ | DRD4 | P21917 | 5/20 | 0.65 |
| ▸ | DRD5 | P21918 | 5/20 | 0.65 |
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
| ▸ | DRD3 | P35462 | 4/20 | 0.65 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525085 | 0.89 | MAOB (1.00) | MAOBMAOASLC6A4DRD1DRD4 | |
| SCHEMBL30634713 | 0.89 | MAOB (1.00) | MAOBMAOASLC6A4DRD1DRD4 | |
| SCHEMBL20232219 | 0.89 | MAOB (0.63) | MAOBMAOASLC6A4DRD1DRD4 | |
| SCHEMBL20214396 | 0.89 | MAOB (0.63) | MAOBMAOASLC6A4DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL30634715 | 0.87 | MAOB (0.96) | MAOBMAOASLC6A4DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL20854708 | 0.87 | MAOB (0.96) | MAOBMAOASLC6A4DRD1DRD4 | |
| SCHEMBL20214588 | 0.82 | MAOA (0.55) | MAOBMAOASLC6A4DRD1DRD4 | |
| SCHEMBL2915552 | 0.82 | MAOA (0.55) | MAOBMAOASLC6A4DRD1DRD4 | |
| SCHEMBL9424882 | 0.82 | MAOB (0.73) | MAOBMAOASLC6A4DRD1DRD4 | |
| Iodide SCHEMBL9425089 | 0.80 | MAOB (0.70) | MAOBMAOASLC6A4DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108688-A1 | PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR NUCLEAR-MEDICAL IMAGING | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2020-06-04 | — | — | WO | disclosed |
| WO-2019154395-A1 | TETRAHYDROISOQUINOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 中国科学院上海药物研究所 | 2019-08-15 | — | — | WO | disclosed |