Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.73 |
| ▸ | RAB7A | P51149 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
| ▸ | PTPRE | P23469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247337 | 0.79 | PTPN1 (0.68) | PTPN1RAB7AKMT2AALDH1A1MAPT | |
| SCHEMBL22655236 | 0.79 | PTPN1 (0.60) | PTPN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21247234 | 0.77 | PTPN1 (0.64) | PTPN1RAB7AKMT2AALDH1A1MAPT | |
| SCHEMBL21260703 | 0.75 | CFTR (0.54) | PTPN1CFTR | |
| SCHEMBL21247200 | 0.75 | PTPN1 (0.61) | PTPN1RAB7AKMT2AALDH1A1MAPT | |
| SCHEMBL21018391 | 0.75 | PTPN1 (0.46) | PTPN1 | |
| SCHEMBL19320871 | 0.74 | PTPN1 (0.55) | PTPN1 | |
| SCHEMBL21261018 | 0.74 | PTPN1 (0.60) | PTPN1RAB7AKMT2AALDH1A1MAPT | |
| SCHEMBL21261016 | 0.74 | PTPN1 (0.60) | PTPN1RAB7AKMT2AALDH1A1MAPT | |
| SCHEMBL21260980 | 0.73 | RAB7A (0.58) | PTPN1RAB7AKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154950-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |