Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21261733 | 0.92 | FURIN (0.40) | FURINF2PRSS1PSEN1PSEN2 | |
| SCHEMBL28539679 | 0.85 | FURIN (0.41) | FURINPRSS1 | |
| SCHEMBL28539678 | 0.85 | FURIN (0.41) | FURINPRSS1 | |
| SCHEMBL28220324 | 0.85 | NMT2 (0.45) | FURINPRSS1NMT2NMT1 | |
| SCHEMBL32679433 | 0.84 | DPP8 (0.41) | — | |
| SCHEMBL30902091 | 0.84 | NMT2 (0.42) | FURINPRSS1NMT2NMT1 | |
| SCHEMBL30456526 | 0.81 | FURIN (0.46) | FURINPRSS1PSEN1PSEN2APH1B | |
| SCHEMBL28545639 | 0.80 | RXFP1 (0.40) | FURIN | |
| SCHEMBL28545636 | 0.80 | RXFP1 (0.40) | FURIN | |
| SCHEMBL9402088 | 0.80 | RXFP1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104851-A4 | BETA-HYDROXYBUTYRYL-AMINO ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 刘成 | 2019-08-15 | — | — | WO | disclosed |