⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388239 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7452837 | 0.96 | CCR5 (0.40) | — | |
| SCHEMBL8657415 | 0.91 | CCR5 (0.43) | — | |
| SCHEMBL8327948 | 0.89 | CCR5 (0.35) | — | |
| SCHEMBL25891553 | 0.89 | CCR5 (0.35) | — | |
| SCHEMBL27316 | 0.84 | — | — | |
| SCHEMBL13878152 | 0.84 | CCR5 (0.38) | — | |
| SCHEMBL15193376 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL2186118 | 0.81 | — | — | |
| SCHEMBL7249921 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 863 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130296237-A1 | Use Of Chloroquine To Treat Metabolic Syndrome | UNIV WASHINGTON (US) | 2013-11-07 | — | — | US | claimed |
| US-8440695-B2 | Use of chloroquine to treat metabolic syndrome | ST JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2013-05-14 | — | — | US | claimed |
| US-20050282872-A1 | Novel thyroid receptor ligands and method II | HANGELAND JON | 2005-12-22 | — | — | US | claimed |
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| US-20040171881-A1 | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | PHARMACIA & UPJOHN COMPANY | 2004-09-02 | — | — | US | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| WO-2001092232-A1 | 4-AMINOQUINOLINES AS ANTIINFECTIVE AGENTS | UFC LTD. (GB) | 2001-12-06 | — | — | WO | claimed |
| EP-0684240-B1 | Hydroxamic acid derivatives with three ring substituents | HOFFMANN LA ROCHE (CH) | 2000-08-02 | — | — | EP | claimed |
| EP-0609010-B1 | A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer | BRIDGESTONE CORP (JP) | 2000-03-15 | — | — | EP | claimed |
| EP-0656353-B1 | Aminochinoline derivates useful in the treatment of malaria | HOFFMANN LA ROCHE (CH) | 1998-06-03 | — | — | EP | claimed |
| US-4522943-A | ANTISECRETORY ANTIULCER AGENT | BRISTOL-MYERS COMPANY (US) | 1985-06-11 | — | — | US | claimed |
| US-4503051-A | ANTIULCER, HISTAMINE H2-ANTAGONIST | BRISTOL-MYERS COMPANY (US) | 1985-03-05 | — | — | US | claimed |
| EP-0099122-A2 | Compositions comprising pepstatin and an histamine H2-receptor antagonist having an enhanced antiulcer activity | Bristol-Myers Company (US) | 1984-01-25 | — | — | EP | claimed |
| US-4385055-A | 2-Acetyl-and 2-propionylpyridine thiosemicarbazones as antimalarials | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1983-05-24 | — | — | US | claimed |
| EP-0005586-B1 | 2,4,6-TRIS-(SUBSTITUTED-AMINO)-S-TRIAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1982-04-28 | — | — | EP | claimed |
| US-4261892-A | ANTIINFLAMMATORY, ANTIARTHRITIC | AMERICAN CYANAMID COMPANY (US) | 1981-04-14 | — | — | US | claimed |
| EP-0005586-A1 | 2,4,6-Tris-(substituted-amino)-S-triazines, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-11-28 | — | — | EP | claimed |
| US-4104380-A | Dibenzyl glycolic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1978-08-01 | — | — | US | claimed |
| US-4022834-A | Antibacterially active hexamethylene-bis-biguanides | A/S FARMACEUTISK INDUSTRI (NO) | 1977-05-10 | — | — | US | claimed |
| US-4013638-A | VULCANIZATION ACCELERATORS, OXIDATION INHIBITORS OF RUBBER | MONSANTO COMPANY (US) | 1977-03-22 | — | — | US | claimed |