Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661024 | 0.81 | HSD17B10 (0.63) | KDM4EALDH1A1HPGDCYP1A2KMT2A | |
| SCHEMBL21274321 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1HPGDCYP1A2HSD17B10 | |
| SCHEMBL3786796 | 0.77 | DHODH (0.48) | KDM4EALDH1A1DHODHKDM6BKDM4A | |
| SCHEMBL8897958 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1HPGDCYP1A2KMT2A | |
| SCHEMBL5610239 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HPGDCYP1A2HSD17B10 | |
| SCHEMBL1195261 | 0.76 | MEN1 (0.57) | KDM4EALDH1A1HPGDCYP1A2KMT2A | |
| SCHEMBL10783918 | 0.76 | MEN1 (0.57) | KDM4EALDH1A1HPGDCYP1A2KMT2A | |
| SCHEMBL16502733 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL28459406 | 0.74 | GRM5 (0.49) | KDM4EALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL29008338 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1CYP1A2KMT2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444401-A1 | NOVEL IMIDAZOPYRIDINE COMPOUND | ONO Pharmaceutical Co., Ltd. (JP) | 2012-04-25 | — | — | EP | claimed |