Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 2/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661024 | 0.90 | HSD17B10 (0.63) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL6378389 | 0.90 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL4856686 | 0.89 | MEN1 (0.49) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL28578355 | 0.88 | KDM4E (0.49) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL27970017 | 0.88 | METAP2 (0.53) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL10783912 | 0.86 | CYP1A2 (0.55) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL722165 | 0.85 | BCAT2 (0.47) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL28928988 | 0.85 | MEN1 (0.46) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL10783918 | 0.85 | MEN1 (0.57) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL8418459 | 0.84 | KDM4E (0.56) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291621-B2 | Substituted biaryl amides C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-11-06 | — | — | US | claimed |
| US-20060178414-A1 | Substituted biaryl amides as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2006-08-10 | — | — | US | claimed |
| EP-1487796-A4 | SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS | NEUROGEN CORP (US) | 2005-11-16 | — | — | EP | claimed |
| EP-1487796-A1 | SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-12-22 | — | — | EP | claimed |
| US-20040048913-A1 | Substituted biaryl amides as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2004-03-11 | — | — | US | claimed |
| WO-2003082826-A1 | SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2003-10-09 | — | — | WO | claimed |
| CN-119639276-A | Ink composition, semiconductor nanoparticle-polymer composite prepared therefrom, electronic device, and display device | 三星电子株式会社 | 2025-03-18 | — | — | CN | disclosed |
| EP-3898181-B1 | PARALLELISED 3D LITHOGRAPHY USING MUTI-BEAM, MULTI-COLOUR LIGHT-INDUCED POLYMERISATION | KARLSRUHER INST TECHNOLOGIE (DE) | 2025-01-01 | — | — | EP | disclosed |
| EP-3898181-A1 | PARALLELISED 3D LITHOGRAPHY USING MUTI-BEAM, MULTI-COLOUR LIGHT-INDUCED POLYMERISATION | Karlsruher Institut für Technologie (DE) | 2021-10-27 | — | — | EP | disclosed |
| CN-211463155-U | Reaction device for producing and preparing phenyl naphthoate compound | 武汉海昕药物研究有限公司 | 2020-09-11 | — | — | CN | disclosed |
| WO-2020126154-A1 | PARALLELISED 3D LITHOGRAPHY USING MUTI-BEAM, MULTI-COLOUR LIGHT-INDUCED POLYMERISATION | Karlsruher Institut für Technologie (DE) | 2020-06-25 | — | — | WO | disclosed |
| CN-109665958-A | A kind of method that ruthenium catalysis prepares polysubstituted 1- naphthoic acid class compound | 广州大学 | 2019-04-23 | — | — | CN | disclosed |
| US-9217053-B2 | Active ester resin, thermosetting resin composition, cured product of same, semiconductor encapsulation material, prepreg, circuit board, and build-up film | DIC CORPORATION (JP) | 2015-12-22 | — | — | US | disclosed |
| US-20050096358-A1 | Substituted biaryl amides as C5A receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2005-05-05 | — | — | US | disclosed |
| EP-0439585-B1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS | MAG GEORG MAYRHOFER & CO OHG (AT) | 1997-10-29 | — | — | EP | disclosed |
| US-5241103-A | Dissolving 1,4-dihydroxy-2-arylnaphthoate containing a dimer by-product in an alcohol/water mixed solvent and isolation of 2-arylnaaphthoate by crystallization | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-31 | — | — | US | disclosed |
| US-5196478-A | Polystyrene, assays | EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) | 1993-03-23 | — | — | US | disclosed |
| US-5162570-A | PROCESS FOR PRODUCING 1,4-DIHYDROXY-2-ARYLNAPHTHOATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0439585-A1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS. | EPIPHARM ALLERGIE SERVICE (AT) | 1991-08-07 | — | — | EP | disclosed |
| WO-1991002768-A1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS | EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) | 1991-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048913-A1 | Substituted biaryl amides as C5a receptor modulators | C5AR1, C5AR2, C3AR1 | MEN1 2253/4885KMT2A 4285/4885ALDH1A1 1494/4885 |
| US-20050096358-A1 | Substituted biaryl amides as C5A receptor modulators | C5AR1, C5AR2, C3AR1 | MEN1 2407/4885KMT2A 4155/4885ALDH1A1 1680/4885 |
| US-20060178414-A1 | Substituted biaryl amides as C5a receptor modulators | C5AR1, C5AR2, C3AR1 | MEN1 2407/4885KMT2A 4155/4885ALDH1A1 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.