Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908929 | 0.95 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13408624 | 0.84 | THRB (0.44) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL700642 | 0.83 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL672102 | 0.83 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2367616 | 0.83 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4950550 | 0.83 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL7157722 | 0.83 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL22166147 | 0.83 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9314009 | 0.83 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9485961 | 0.83 | THRB (0.79) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190248942-A1 | MATERIAL NON-ADHESIVE TO BIOLOGICAL SUBSTANCE, CURABLE COMPOSITION, AND ARTIFICIAL ORGAN AND MEDICAL INSTRUMENT USING SAME | FUJIFILM CORPORATION (JP) | 2019-08-15 | — | — | US | disclosed |