Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 20/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.56 |
| ▸ | GABRD | O14764 | 19/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 19/20 | 0.56 |
| ▸ | GABRP | O00591 | 18/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 18/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 18/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 18/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 18/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 18/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 18/20 | 0.56 |
| ▸ | GABRE | P78334 | 18/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 18/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 18/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 18/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 18/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21134625 | 0.92 | GABRA1 (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL19655746 | 0.92 | GABRA1 (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL22782935 | 0.92 | GABRA1 (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL25699273 | 0.92 | GABRA1 (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL20924552 | 0.92 | GABRA1 (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL19655748 | 0.92 | GABRA1 (0.62) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL29904114 | 0.90 | GABRA1 (0.56) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL22576792 | 0.87 | GABRA1 (0.54) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL28899592 | 0.87 | GABRA1 (0.56) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL28461274 | 0.87 | GABRA1 (0.56) | GABRA1GABRB2GABRDGABRA4GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3750908-A1 | STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154257-A1 | STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF | 江苏豪森药业集团有限公司 | 2019-08-15 | — | — | WO | disclosed |