Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451651 | 0.84 | LMNA (0.46) | HSD17B10LMNAGAAKDM4EALDH1A1 | |
| SCHEMBL16955284 | 0.84 | PARP1 (0.40) | HSD17B10LMNAGAAKDM4EALDH1A1 | |
| SCHEMBL7405863 | 0.82 | CA1 (0.40) | LMNAGAAKDM4ETSHRALDH1A1 | |
| SCHEMBL4316500 | 0.81 | CA1 (0.50) | LMNAKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL21268416 | 0.78 | ELANE (0.49) | HSD17B10RAB9AELANEMAPTPOLB | |
| SCHEMBL417129 | 0.78 | HSD17B10 (0.57) | HSD17B10LMNAGAAKDM4ETSHR | |
| SCHEMBL1543332 | 0.78 | HSD17B10 (0.57) | HSD17B10LMNAGAAKDM4ETSHR | |
| SCHEMBL4316367 | 0.78 | PLA2G4B (0.49) | HSD17B10TSHRRAB9AMAPTTDP1 | |
| SCHEMBL9203640 | 0.77 | CYP3A4 (0.53) | HSD17B10LMNAGAAKDM4EALDH1A1 | |
| SCHEMBL16959932 | 0.77 | LMNA (0.53) | HSD17B10LMNAGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |