SCHEMBL21268352

SCHEMBL21268352

CCCCOc1cc[c]cc1OCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
MAPT P10636 2/20 0.36
GAA P10253 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
CASP1 P29466 1/20 0.36
HTT P42858 1/20 0.36
CASP7 P55210 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
LTA4H P09960 4/20 0.35
ESR1 P03372 1/20 0.35
NR5A1 Q13285 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677792 0.96 CYP1A2 (0.44) CYP1A2CYP2C9CYP2C19GAALTA4H
SCHEMBL687572 0.94 MAPT (0.39) CYP1A2CYP2C9CYP2C19MAPTGAA
SCHEMBL7110497 0.91 NR5A1 (0.44) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL21268380 0.91 L3MBTL1 (0.42) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL27265460 0.91 NR5A1 (0.44) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL677544 0.91 MEN1 (0.39) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL7111290 0.89 NR5A1 (0.42) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL17416897 0.89 NR5A1 (0.42) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL3458097 0.89 NR5A1 (0.42) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL1451260 0.89 NR5A1 (0.42) CYP1A2CYP2C9CYP2C19MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-B1 HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2019-08-21 EP disclosed