Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268334 | 0.92 | ELANE (0.40) | ELANECA2MAPKAPK2THRBKDM1A | |
| SCHEMBL21268213 | 0.88 | ELANE (0.44) | ELANECA2KDM1A | |
| SCHEMBL21268366 | 0.85 | ELANE (0.44) | ELANECA2KDM1APPARGPPARA | |
| SCHEMBL21268207 | 0.83 | ELANE (0.53) | ELANECA2MAPKAPK2KDM1A | |
| SCHEMBL21268281 | 0.82 | ELANE (0.41) | ELANECA2KDM1A | |
| SCHEMBL21268208 | 0.81 | ELANE (0.43) | ELANECA2MAPKAPK2KDM1AALDH1A1 | |
| SCHEMBL21268442 | 0.81 | ELANE (0.45) | ELANECA2MAPKAPK2KDM1ANPC1 | |
| SCHEMBL16957415 | 0.80 | CYP4F2 (0.41) | PTPN1PTPN11THRBALOX5ALDH1A1 | |
| SCHEMBL21268164 | 0.79 | ELANE (0.49) | ELANECA2KDM1A | |
| SCHEMBL21268361 | 0.77 | ELANE (0.47) | ELANECA2MAPKAPK2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |