Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17035684 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL1863853 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL1133020 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL117760 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL17336921 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL23365822 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL12980679 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL17627766 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL20912969 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL117759 | 0.89 | MAPT (0.58) | MAPTMAPK1KMT2ACYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444846-B1 | Method for rebalancing a multicomponent solvent solution | DU PONT (US) | 2015-04-22 | — | — | EP | disclosed |
| US-8349185-B2 | Method for rebalancing a multicomponent solvent solution | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120100489-A1 | METHOD FOR REBALANCING A MULTICOMPONENT SOLVENT SOLUTION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-26 | — | — | US | disclosed |
| EP-2444846-A2 | Method for rebalancing a multicomponent solvent solution | E. I. du Pont de Nemours and Company (US) | 2012-04-25 | — | — | EP | disclosed |