SCHEMBL17035684

SCHEMBL17035684

CC(=O)OC1C[C@@H]2CC[C@@]1(C)C2(C)C

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
MAPK1 P28482 2/20 0.58
KMT2A Q03164 2/20 0.58
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
MEN1 O00255 1/20 0.54
CYP19A1 P11511 2/20 0.53
CYP2C19 P33261 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133020 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA
SCHEMBL12980679 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA
SCHEMBL17336921 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA
SCHEMBL117759 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA
SCHEMBL1863853 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA
SCHEMBL23365822 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA
SCHEMBL17627766 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA
SCHEMBL117760 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA
SCHEMBL20912969 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA
SCHEMBL1863854 1.00 MAPT (0.58) MAPTMAPK1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9408407-B2 Compounds, compositions, and methods for reducing or eliminating bitter taste CHROMOCELL CORPORATION (US) 2016-08-09 US disclosed
US-20150237900-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE CHROMOCELL CORP (US) 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150237900-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE TAS2R5, TAS2R20, TAS2R10 MAPT 4340/4885MAPK1 3212/4885KMT2A 2441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.