SCHEMBL2127015

SCHEMBL2127015

OP(O)c1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.48
ALDH1A1 P00352 7/20 0.46
HSD17B10 Q99714 5/20 0.46
CYP2A6 P11509 3/20 0.46
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
HPGD P15428 3/20 0.42
CYP3A4 P08684 2/20 0.42
KEAP1 Q14145 1/20 0.42
HPRT1 P00492 1/20 0.42
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
TP53 P04637 1/20 0.40
ALOX15 P16050 1/20 0.40
CDC25B P30305 1/20 0.40
ATM Q13315 1/20 0.40
PTPN22 Q9Y2R2 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517685 0.81 ALDH1A1 (0.53) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL9327672 0.81 CYP1A2 (0.44) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL135987 0.79 ALDH1A1 (0.50) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL29390280 0.79 ALDH1A1 (0.50) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL11826715 0.77 ALDH1A1 (0.48) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL15658735 0.77 ALDH1A1 (0.48) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL11861469 0.77 ALDH1A1 (0.48) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL21111749 0.76 ALDH1A1 (0.42) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL1107761 0.75 ALDH1A1 (0.48) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL21609886 0.75 ALDH1A1 (0.46) CYP1A2ALDH1A1HSD17B10CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2112213-B1 Organic electroluminescence device, novel platinum complex compound and novel compound capable of being a ligand thereof FUJIFILM CORP (JP) 2012-07-04 EP disclosed
EP-1249731-B1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORP (JP) 2012-04-25 EP disclosed
EP-2112213-A2 Organic electroluminescence device, novel platinum complex compound and novel compound capable of being a ligand thereof FUJIFILM Corporation (JP) 2009-10-28 EP disclosed
US-6858373-B2 Photosensitive composition and negative working lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2005-02-22 US disclosed
US-20030091933-A1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORPORATION (JP) 2003-05-15 US disclosed
EP-1249731-A2 Photosensitive composition and negative working lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-10-16 EP disclosed
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
US-5861107-A ESTER INTERCHANGE OF 1,3-PROPANEDIOL COMPOUNDS WITH CARBONIC ACID ESTERS; DISTILLATIVE DEPOLYMERIZATION; CATALYSIS WITH TITANIUM OR ZIRCONIUM COMPOUND; PHOSPHORUS OR SULFUR COMPOUND STABILIZER BAYER AKTIENGESELLSCHAFT (DE) 1999-01-19 US disclosed
US-5250393-A Containing diazo resin and alkali metal or ammonium silicate FUJI PHOTO FILM CO., LTD. (JP) 1993-10-05 US disclosed
EP-0492959-A1 Method for developing presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1992-07-01 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed
EP-0036278-B1 POLYPHENYLENE ETHER RESIN COMPOSITION OF IMPROVED HEAT STABILITY AND SHAPED ARTICLES THEREOF MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-06-19 EP disclosed
EP-0036278-A1 Polyphenylene ether resin composition of improved heat stability and shaped articles thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1981-09-23 EP disclosed