1,4-Butanediol

1,4-Butanediol

SCHEMBL21271

C(OCC1CO1)C1CO1.OCCCCO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 9/20 0.47
TDP1 Q9NUW8 3/20 0.47
MAPK1 P28482 1/20 0.46
TP53 P04637 2/20 0.36
CYP3A4 P08684 2/20 0.36
HIF1A Q16665 1/20 0.33
GLA P06280 1/20 0.31
PRKD3 O94806 1/20 0.30
PRKCG P05129 1/20 0.30
PRKCB P05771 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCH P24723 1/20 0.30
PRKCI P41743 1/20 0.30
PRKCE Q02156 1/20 0.30
PRKCQ Q04759 1/20 0.30
PRKCZ Q05513 1/20 0.30
PRKCD Q05655 1/20 0.30
PRKD1 Q15139 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL29288525 1.00 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
1,4-Butanediol SCHEMBL28947004 1.00 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
1,4-Butanediol SCHEMBL28947007 1.00 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL12805058 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL262588 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL23668238 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL890476 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL21834094 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL20543293 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3057140 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 24478 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636406-B2 Biological prosthesis and methods of production and use ROSIVO LLC (US) 2026-05-26 US claimed
US-12637584-B2 Waterborne polyurethane-epoxy resin based primer composition and its preparation method thereof BASF COATINGS GMBH (DE) 2026-05-26 US claimed
US-20260137724-A1 COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING LIGAMENT OR TENDON DISEASES HANS BIOMED CORP (KR) 2026-05-21 US claimed
US-20260142183-A1 Protected Sulfur Cathode for Alkali Metal-Sulfur Secondary Battery and Manufacturing Method HONEYCOMB BATTERY COMPANY (US) 2026-05-21 US claimed
US-12630669-B2 Waterborne epoxy curing agent EVONIK OPERATIONS GMBH (DE) 2026-05-19 US claimed
WO-2026100984-A1 SOLVENT-FREE EPOXY COATING COMPOSITION 주식회사 케이씨씨 2026-05-15 WO claimed
WO-2026101354-A1 COMPOSITE NANOWEB MATERIAL COMPRISING DECELLULARIZED EXTRACELLULAR MATRIX, MANUFACTURING METHOD THEREFOR, AND THERAPEUTIC MATERIAL INCLUDING SAME 한국생산기술연구원 2026-05-15 WO claimed
US-20260132228-A1 METHOD FOR PREPARING A CROSS-LINKED HYALURONIC ACID GEL QUANTUM BEAUTY KOZMETK ANONM RKET (TR) 2026-05-14 US claimed
EP-4131549-B1 CAPSULE FOR LITHIUM-SULFUR SECONDARY BATTERY, AND LITHIUM-SULFUR SECONDARY BATTERY COMPRISING SAME LG ENERGY SOLUTION LTD (KR) 2026-05-13 EP claimed
EP-3433284-B1 MODIFIED HYALURONIC ACID, METHOD FOR MAKING SAME AND USES THEREOF MERZ PHARMA GMBH & CO KGAA (DE) 2026-05-06 EP claimed
EP-0003258-B1 PREPARATION OF N-CHLOROIMIDES AND A NOVEL N-CHLOROIMIDE ELI LILLY AND COMPANY (US) 1982-01-13 EP claimed
US-4286964-A Polyfunctional epoxides and halohydrins used as bridging groups to bind aromatic amine group-containing alcohols and thiols to hydroxyl bearing substrates SEED BRIAN S 1981-09-01 US claimed
EP-0027377-A1 Derivatives of hydroxyl-bearing substrates, process for their preparation and a method of application Seed, Brian Sarsfield (US) 1981-04-22 EP claimed
US-4228438-A Video jet printer process with radiation cured ink BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1980-10-14 US claimed
US-4174229-A SPRAYABLE FIREPROOFING MATERIAL PPG INDUSTRIES, INC. (US) 1979-11-13 US claimed
US-4174228-A SPRAYABLE FIREPROOFING MATERIAL PPG INDUSTRIES, INC. (US) 1979-11-13 US claimed
EP-0003258-A1 Preparation of N-chloroimides and a novel N-chloroimide ELI LILLY AND COMPANY (US) 1979-08-08 EP claimed
US-4099837-A ACRYLATE-EPOXY POLYMER BELL TELEPHONE LABORATORIES, INCORPORATED (US) 1978-07-11 US claimed
US-4055541-A Reaction products of non-cycloaliphatic epoxy resins and amine-terminated liquid polymers and process for preparation thereof THE B. F. GOODRICH COMPANY (US) 1977-10-25 US claimed
US-4054498-A TITANIUM DIOXIDE, CATALYST AMERICAN CAN COMPANY (US) 1977-10-18 US claimed