1,4-Butanediol

1,4-Butanediol

SCHEMBL28947007

C(OCC1CO1)C1CO1.OCCCCO.OCCCCO.OCCCCO

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 9/20 0.47
TDP1 Q9NUW8 3/20 0.47
MAPK1 P28482 1/20 0.46
TP53 P04637 2/20 0.36
CYP3A4 P08684 2/20 0.36
HIF1A Q16665 1/20 0.33
GLA P06280 1/20 0.31
PRKD3 O94806 1/20 0.30
PRKCG P05129 1/20 0.30
PRKCB P05771 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCH P24723 1/20 0.30
PRKCI P41743 1/20 0.30
PRKCE Q02156 1/20 0.30
PRKCQ Q04759 1/20 0.30
PRKCZ Q05513 1/20 0.30
PRKCD Q05655 1/20 0.30
PRKD1 Q15139 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL29288525 1.00 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
1,4-Butanediol SCHEMBL28947004 1.00 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
1,4-Butanediol SCHEMBL21271 1.00 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL12805058 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL262588 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL23668238 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL890476 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL21834094 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL20543293 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3057140 0.98 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115668484-A Liquid compression molding material 纳美仕有限公司 2023-01-31 CN disclosed