Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127150 | 1.00 | CCR2 (0.75) | CCR2KCNH2 | |
| SCHEMBL2127182 | 0.92 | CCR2 (0.72) | CCR2KCNH2 | |
| SCHEMBL2127181 | 0.92 | CCR2 (0.72) | CCR2KCNH2 | |
| SCHEMBL5234891 | 0.91 | CCR2 (0.79) | CCR2KCNH2 | |
| SCHEMBL5234550 | 0.90 | CCR2 (0.85) | CCR2KCNH2 | |
| SCHEMBL743364 | 0.90 | CCR2 (0.85) | CCR2KCNH2 | |
| SCHEMBL745106 | 0.89 | CCR2 (0.81) | CCR2KCNH2 | |
| SCHEMBL746736 | 0.89 | CCR2 (0.70) | CCR2KCNH2 | |
| SCHEMBL2127387 | 0.88 | CCR2 (0.80) | CCR2KCNH2 | |
| SCHEMBL2127390 | 0.88 | CCR2 (0.80) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362003-B2 | 3-aminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2013-01-29 | — | — | US | claimed |
| EP-1565436-B1 | 3-AMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2012-04-25 | — | — | EP | claimed |