⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536879 | 0.80 | — | — | |
| SCHEMBL218726 | 0.53 | ALDH1A1 (0.54) | — | |
| SCHEMBL2534989 | 0.52 | ALDH1A1 (0.32) | — | |
| SCHEMBL18082013 | 0.52 | ALDH1A1 (0.30) | — | |
| SCHEMBL1323446 | 0.51 | ALDH1A1 (0.50) | — | |
| SCHEMBL8733589 | 0.51 | ALDH1A1 (0.61) | — | |
| SCHEMBL30519495 | 0.51 | ALDH1A1 (0.50) | — | |
| SCHEMBL20781 | 0.51 | — | — | |
| SCHEMBL1332087 | 0.51 | — | — | |
| SCHEMBL22895988 | 0.49 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135658-A | Bridged nucleoside and nucleotide using the same | 国立大学法人大阪大学 | 2022-09-30 | — | — | CN | claimed |
| WO-2022004388-A1 | 5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE USING SAME | 国立大学法人大阪大学 | 2022-01-06 | — | — | WO | claimed |
| CN-113412268-A | 5' -modified nucleoside and nucleotide using the same | 国立大学法人大阪大学 | 2021-09-17 | — | — | CN | claimed |
| WO-2020158910-A1 | 5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE USING SAME | 国立大学法人大阪大学 | 2020-08-06 | — | — | WO | claimed |
| EP-3109254-B1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | UNIV OSAKA (JP) | 2018-04-11 | — | — | EP | claimed |
| EP-1152009-B2 | NOVEL NUCLEOSIDES AND OLIGONUCLEOTIDE ANALOGUES | DAIICHI SANKYO CO LTD (JP) | 2017-09-06 | — | — | EP | claimed |
| US-9611479-B2 | Crosslinked nucleoside and nucleotide | OSAKA UNIVERSITY (JP) | 2017-04-04 | — | — | US | claimed |
| EP-2899197-B1 | OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEOSIDE HAVING GUANIDINE BRIDGE | UNIV OSAKA (JP) | 2017-03-22 | — | — | EP | claimed |
| US-20170044528-A1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | OSAKA UNIVERSITY (JP) | 2017-02-16 | — | — | US | claimed |
| EP-3109254-A1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | OSAKA UNIVERSITY (JP) | 2016-12-28 | — | — | EP | claimed |
| US-20150266917-A1 | OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEOSIDE HAVING GUANIDINE BRIDGE | OSAKA UNIVERSITY (JP) | 2015-09-24 | — | — | US | claimed |
| EP-2899197-A1 | OLGIONUCLEOTIDE AND ARTIFICIAL NUCLEOSIDE HAVING GUANIDINE BRIDGE | Osaka University (JP) | 2015-07-29 | — | — | EP | claimed |
| EP-1661905-B9 | NOVEL ARTIFICIAL NUCLEIC ACIDS OF N-O BOND CROSSLINKAGE TYPE | IMANISHI TAKESHI (JP) | 2012-12-19 | — | — | EP | claimed |
| EP-1661905-B1 | NOVEL ARTIFICIAL NUCLEIC ACIDS OF N-O BOND CROSSLINKAGE TYPE | IMANISHI TAKESHI (JP) | 2012-04-25 | — | — | EP | claimed |
| US-7615619-B2 | Nucleoside analogues and oligonucleotide derivative comprising nucleotide analogue thereof | TAKESHI IMANISHI (JP) | 2009-11-10 | — | — | US | claimed |
| EP-1152009-B1 | NOVEL NUCLEOSIDES AND OLIGONUCLEOTIDE ANALOGUES | SANKYO CO (JP) | 2005-01-26 | — | — | EP | claimed |
| EP-1201678-B1 | NOVEL BICYCLONUCLEOSIDE ANALOGUES | SANKYO CO (JP) | 2004-09-22 | — | — | EP | claimed |
| CN-112513062-B | Oligonucleotide-containing small cell lung cancer therapeutic agent | 国立大学法人大阪大学 | 2024-05-10 | — | — | CN | disclosed |
| US-4968674-A | Antiviral carbocyclic purine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | disclosed |