Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983225 | 0.89 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL1339997 | 0.86 | HCRTR1 (0.46) | HCRTR1HCRTR2ALDH1A1GAATSHR | |
| SCHEMBL2128188 | 0.85 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL2128222 | 0.85 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL2125907 | 0.84 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL2126399 | 0.84 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL2127411 | 0.83 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL2127620 | 0.83 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL984532 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL984531 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247586-B1 | 2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-04-25 | — | — | EP | disclosed |