Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 17/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983225 | 0.89 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2128148 | 0.86 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL3415736 | 0.86 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL2127224 | 0.85 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL2125964 | 0.84 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL984531 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL984532 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL2125907 | 0.82 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL2127620 | 0.81 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2125388 | 0.80 | HCRTR1 (0.45) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247586-B1 | 2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-04-25 | — | — | EP | claimed |