Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.79 |
| ▸ | PRKCG | P05129 | 6/20 | 0.78 |
| ▸ | PRKCB | P05771 | 5/20 | 0.78 |
| ▸ | PRKCH | P24723 | 5/20 | 0.78 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.78 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.78 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.78 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.78 |
| ▸ | PRKCI | P41743 | 4/20 | 0.78 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.78 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.78 |
| ▸ | USP2 | O75604 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922839 | 1.00 | PRKCA (0.79) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL312634 | 1.00 | PRKCA (0.79) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL18627982 | 1.00 | PRKCA (0.79) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL8192421 | 1.00 | PRKCA (0.79) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL22171801 | 1.00 | PRKCA (0.79) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL21578359 | 1.00 | PRKCA (0.79) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL18210530 | 1.00 | PRKCA (0.79) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL892726 | 1.00 | PRKCA (0.79) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL16904300 | 1.00 | PRKCA (0.79) | PRKCAPRKCGPRKCBPRKCHPRKCE | |
| SCHEMBL18210529 | 0.99 | PRKCA (0.81) | PRKCAPRKCGPRKCBPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10948480-B2 | Immunity to folate receptors | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-03-16 | — | — | US | disclosed |
| US-9915646-B2 | Immunity to folate receptors | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2018-03-13 | — | — | US | disclosed |
| US-20160131638-A1 | IMMUNITY TO FOLATE RECEPTORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-05-12 | — | — | US | disclosed |
| US-9243033-B2 | Immunity to folate receptors | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2016-01-26 | — | — | US | disclosed |
| US-20140212443-A1 | IMMUNITY TO FOLATE RECEPTORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2014-07-31 | — | — | US | disclosed |
| US-8486412-B2 | Immunity to folate receptors | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2013-07-16 | — | — | US | disclosed |
| EP-1356277-B1 | METHOD FOR ALTERING CELL FATE | KYOWA HAKKO KIRIN CO LTD (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-20100272741-A1 | IMMUNITY TO FOLATE RECEPTORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2010-10-28 | — | — | US | disclosed |
| US-7736895-B2 | Methods for altering cell fate | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-06-15 | — | — | US | disclosed |
| US-7491534-B2 | Methods for altering cell fate to generate T-cells specific for an antigen of interest | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2009-02-17 | — | — | US | disclosed |
| EP-0181455-B2 | Use of preparations containing interferon-gamma (IFN-gamma) for systematically treating various human diseases at a low dosage | BOEHRINGER INGELHEIM INT (DE) | 2000-05-31 | — | — | EP | disclosed |
| EP-0373335-B1 | Serine protease inhibitor proteins, medicaments containing them, DNA sequences coding for these proteins and methods for producing these proteins, medicaments and DNA sequences | GRUENENTHAL GMBH (DE) | 1997-12-10 | — | — | EP | disclosed |
| EP-0767840-A2 | METHOD FOR INTRODUCING FOREIGN MATTER INTO HIGHER EUKARYOTIC CELLS | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1997-04-16 | — | — | EP | disclosed |
| WO-1995033062-A2 | METHOD FOR INTRODUCING FOREIGN MATTER INTO HIGHER EUKARYOTIC CELLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 1995-12-07 | — | — | WO | disclosed |
| EP-0373335-A2 | Serine protease inhibitor proteins, medicaments containing them, DNA sequences coding for these proteins and methods for producing these proteins, medicaments and DNA sequences | Grünenthal GmbH (DE) | 1990-06-20 | — | — | EP | disclosed |
| EP-0180737-B1 | USE OF INTERFERON GAMMA (IFN-GAMMA) FOR THE PRODUCTION OF PREPARATIONS FOR TREATING RHEUMATIC DISEASES | BIOFERON BIOCHEM SUBSTANZ (DE) | 1989-08-23 | — | — | EP | disclosed |
| EP-0205629-A1 | Use of preparations containing gamma interferon (IFN-gamma) for treating rheumatic diseases | BIOFERON Biochemische Substanzen GmbH & Co i.K. (DE) | 1986-12-30 | — | — | EP | disclosed |
| EP-0181455-A2 | Use of preparations containing interferon-gamma (IFN-gamma) for systematically treating various human diseases at a low dosage | Dr. Rentschler Biotechnologie GmbH (DE) | 1986-05-21 | — | — | EP | disclosed |
| EP-0180737-A2 | Use of interferon gamma (IFN-gamma) for the production of preparations for treating rheumatic diseases | Dr. Rentschler Biotechnologie GmbH (DE) | 1986-05-14 | — | — | EP | disclosed |
| EP-0177910-A2 | Use of preparations containing gamma-interferon (IFN-gamma) for systematically treating various human diseases at a low dosage | BIOFERON Biochemische Substanzen GmbH & Co i.K. (DE) | 1986-04-16 | — | — | EP | disclosed |